Progesterone shots are often recommended for women who’ve had difficulty carrying a baby to full term. The fertility medication is designed to prevent early labor and gives your body, and your baby, a chance to have a normal pregnancy. Babies born prematurely often face a myriad of developmental issues, and if born too early, may not survive. Progesterone works by preventing contractions from occurring and is usually recommended during the second trimester (16-20 weeks). These are given into your muscle, usually in your hip or thigh. Like any type of fertility drug, there are some side effects you should be aware of when receiving these shots. These are the top ten side effects most experienced by women taking the progesterone shots for a higher risk pregnancy. The good news is most women only have to take it for a week or so.

Breast Tenderness

Progesterone is a hormone and like most hormones it affects your reproductive organs. Breast tenderness is to be expected. However, the tenderness should be of the sort normally experienced with your menstrual cycle and not debilitating. If it is uncomfortable, place warm wash cloths on breasts, or alternatively break out the frozen bag of peas. However, lumps in your breast are NOT normal, so if you feel that happening, call your doctor.

Headache

You may experience a slight headache when you start taking the progesterone medication, but it should go away over time. As a fertility medication, it is meant to support the pregnancy rather than bring about fertility, but like other types of fertility meds it can give you a headache. This should not be a severe headache.

Dizziness

Progesterone shots have caused dizziness in some women, so if you are going to the doctor to receive the injections make sure you have someone to drive you home. At least until you know how the medication affects you.

Weight Change

You may experience a slight weight gain or loss with this fertility medication, but it should not be significant. If you experience significant weight changes, then contact your doctor immediately.

Breakouts

Hormones are great for many things, and acne isn’t one of them. However, you may experience breakouts from progesterone treatments. Usually you can treat these with over the counter meds, but to make sure speak with your doctor before doing so.

Nausea

Feeling a little urpy is completely normal with this fertility medication and almost everyone experiences this to some degree. What isn’t normal is projectile vomiting or an inability to keep food down for days on end.

Hair Growth or Loss

No, you won’t go bald, nor will your tresses grow like Rapunzel’s but progesterone can cause you to grow more hair on your face and even on your body. Sadly, it can also cause you to lose hair on your scalp. However, progesterone should not make you lose copious amounts, nor should you start looking like a grizzly bear.

Injection Site Pain

Progesterone shots, by their very nature, are going to cause a small amount of pain. Some swelling, slight redness and even a bit of itchiness is typical. Try icing it down. If the pain persists or gets worse, then call your doctor.

Bleeding of Any Sort

This is not a typical side effect and if you have any type of bleeding with the progesterone shot, such as break through bleeding, vaginal discharge, spotting, then call your doctor immediately.

Discolored Skin

This is another side effect of progesterone that is not typical, and if you experience it, seek assistance immediately. This can include dark patches on your skin or face.

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