Bravelle 75 IU is prescribed for the development of multiple follicles during the cycles of Assisted Reproductive Technologies in patients who have received primary suppression previously. It is a highly purified preparation of the hFSH (human follicle stimulating hormone), and contains 75 IU FSH with 2 % luteinizing hormone activity. It stimulates the development of eggs in women whose ovaries are healthy, but are not able to develop eggs. Bravelle is not used by patients who are suffering from the ovarian failure.
Bravelle is a lyophilized, sterile powder which is intended for the intramuscular or subcutaneous injection after reconstitution with 0.9% sodium-chloride injection. When administered for seven to twelve days, the medicine causes ovarian growth in patients. In most cases, it results into follicular maturation and growth. When enough follicle maturation has occurred, the hCG should be given to stimulate ovulation. However, before treatment with Bravelle 75 IU, a thorough endocrinologic and gynecologic evaluation needs to be performed. The use of this medicine is contradicted in patients who have high FSH levels, uncontrolled adrenal and thyroid dysfunction, abnormal bleeding, pituitary tumor, and the presence of any fertility cause other than anovulation. So, it must be taken only after the prescription of physicians who are familiar with infertility related problems.
Bravelle 75 IU should be stored at room temperature, somewhere between 37 0 F and 77 0 F. It must be protected from light, and used immediately after the reconstitution. Keep in mind that the medication cannot be mixed in advance, and once it’s mixed, it should be used within fifteen minutes.
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